Alpha Lipoic Acid
(ALA) is a unique nutrient shown to have a potent effect on glucose disposal. It is also a natural antioxidant with free radical scavenging abilities as well as the ability to regenerate oxidized antioxidants. This actually makes other antioxidants more potent.
ALA also increases the levels of intra-cellular glutathione. Glutathione has been shown to enhance recovery from heavy training by reducing intra-cellular damage.
ALA's ability to enhance glucose uptake is a very exciting effect that could enhance other nutrient distribution. By mimicking insulin, ALA increases uptake of glucose into the muscle cell by 65%. This glucose transport stimulation is accomplished through Lipoic Acid's participation in the insulin signaling pathway. Lipoic Acid provokes an upward shift of the glucose-insulin dose-response curve. This is an important function that enhances muscle cell nutrient uptake and protein turnover.
ALA may also increase creatine's ability to enter the muscle cell further enhancing creatine's muscle building
effects. ALA mimics insulin. It works in the same way that insulin does by shuttling
glucose into the muscle cells.
It is recommended at 500mg/day in divided doses.