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Old 20-Feb-03, 11:45 AM   #1
Helene
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Confused about Glutamine...


I'm confused about glutamine. Do I take it or not? I heard that it's not necessary..then hear that everybody takes it. Am I missing something if I don't take it. Does everyone of you take it? What does it do exactly?

And is it better pills or powder? I think the powder is less expensive ehn?

Right now the supplements I take are:

multivitamin
vitamine C, E
Protein powder

And I'm still debating about the glutamine..

Please tell me your thoughts
thanks,
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Old 20-Feb-03, 12:25 PM   #2
Todd
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Well, Helene...I am kinda in the same boat....for years I have heard that Glutamine was a great supplement ...and it has ranked right up there with creatine (for different reasons of course) ..but nonetheless, I have always heard and thought it was a great and effective supplement at boosting the immune system, and helping to spare the breakdown (catabolism) of your hard earned muscle. Then, I start seeing posts on here (like you) where people are saying it is completely useless as a supplement and that it doesn't do anything, except put a small dent in your wallet.

Now, I personally have taken glutamine religiously for a while up until 2 weeks ago. And I have successfully been able to keep the muscle I have gained (I am a hardgainer and have to take in stupid amounts of food and do everything perfectly just to add a pound of muscle) and have been happy with the way things are going for me. So, I just recently stopped taking it and I am going to wait a month and re-assess my progress to see if there is any difference at all. Then, I am going to start taking it again...because besides this forum, I have not seen any other information to state that glutamine is useless...and I don't go by what I read...I go by actually doing it for myself to see if it works/doesn't work.

I believe that glutamine does aid in preventing muscle loss and helping out with many other smaller functions within the body....it is the most required amino acid within the body and your body is continuously breaking it down during daily functions.....there have been too many previous studies done to show and prove all of this and I don't see how all that could just change suddenly and become false.

I don't know that my answer here will help make your desicion to take/not take it any easier, but, that is what I know and have to say about it based on my use of it. That is my 2 cents worth!
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Old 20-Feb-03, 12:30 PM   #3
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Thanks, for your reply Todd. I asked a trainer yesterday at the gym and he said that yes it's good, it boosts your immune system and it helps in muscle making..but he said that it promotes cancer cells (something like that) so if you had cancer before or have alot of cancer in your family to not take it..Anyway..I'll think about it.
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Old 20-Feb-03, 12:34 PM   #4
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You're welcome Helene!
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Old 20-Feb-03, 12:43 PM   #5
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Great post Todd, I had the same feeling as Helene -- popular opinion on the subject seems quite polarized, it's easy to lose perspective...
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Old 20-Feb-03, 12:45 PM   #6
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cancer?! that is a new one on me. i take 30g a day and i use the powder..it is cheaper when taking as much as i do. as for whether it is worth it or not..i think so and i base my answer on research and what it has done for me.

p.s. don't listen to pt's. they usually don't have a clue as to what they are talking about.
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Old 20-Feb-03, 12:55 PM   #7
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Yah, I have never heard anything about cancer and glutamine...I mean, you hear about everything causing cancer or might cause it, then you read in a paper a month later that it is not cancer causing...it's like make up your mind! LOL!

I take my glutamine in powder form as it is absorbed more quickly this way.
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Old 20-Feb-03, 04:07 PM   #8
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Quote:
Originally posted by Helene
Thanks, for your reply Todd. I asked a trainer yesterday at the gym and he said that yes it's good, it boosts your immune system and it helps in muscle making..but he said that it promotes cancer cells (something like that) so if you had cancer before or have alot of cancer in your family to not take it..Anyway..I'll think about it.

That trainer must be ISSA certified


Sounds clueless to me. Maybe he can explain to you the physiological process in which glutamine is muscle sparing? Doubt he can do that. Maybe he can explain to you the physiological process in which glutamine boosts either the specific or non spefici immune system... I know he cant do that. Truth is, not many people can. Why? Because it doesnt occur like people want to think.

Check this thread:

http://www.discussfitness.com/showth...ight=glutamine


Some people swear by it, most dont. Let me explain why people swear by it...... as most of you know, glutamine is rather expensive. Now, if glutamine is the most abundant free form amino acid in the body (which it is) why does it cost so much? 1. The fancy bottles and ads put into selling the glutamine is the main reason. Placebo plays a huge role in people thinking glutamine works. You spend so much money on this crap, you want to think so bad that you didnt waste your money, so you convince yourself it works. Hate to be the bearer of bad news....but the glutamine is 99% worthless in your body.
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Old 20-Feb-03, 04:15 PM   #9
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Everyone has their own opinion and sources to base their opinion on...
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Old 20-Feb-03, 04:31 PM   #10
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I think Glutamine stole YellowJ's bike when he was little or something...
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Old 20-Feb-03, 05:24 PM   #11
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Originally posted by -TDS-
I think Glutamine stole YellowJ's bike when he was little or something...
Yes, that and my money
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Old 20-Feb-03, 05:25 PM   #12
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Originally posted by Todd
Everyone has their own opinion and sources to base their opinion on...
Yes and some have legit sources that are unbiased and done by major universities, not paid for by Optimum Nutrition, EAS or Prolabs
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Old 20-Feb-03, 05:49 PM   #13
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I never said opinions/sources I (or anyone else) was talking about came from any supplement company.
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Old 20-Feb-03, 06:02 PM   #14
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Originally posted by Todd
I never said opinions/sources I (or anyone else) was talking about came from any supplement company.

Come to think of it, Ive never even seen your sources....
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Old 20-Feb-03, 06:18 PM   #15
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What kinds of stress cause glutamine depletion?

"Research is showing that glutamine depletion caused by stress can be activated by something as minor as a common cold and the level of depletion increases with the severity of the disease. Patients undergoing surgery, burn victims, those suffering acute trauma, as well as HIV and cancer patients will all find their glutamine levels severely depleted by their condition.
The important thing, as fitness enthusiasts, is to remember that stress related glutamine depletion does not only occur with illness, but also occurs due to stress caused by exercise.
Glutamine and it’s role in bodybuilding and exercise.
Intensive exercise will disrupt immune function, increase lactic acid and ammonium levels. High levels of ammonia can effect muscle function. Within the first five minutes of exercise glutamine levels will rise and catabolic hormones are released. But, the bad news for exercisers doesn’t stop there, because even at the conclusion of the exercise session the muscles will continue to release glutamine causing a severe depletion situation. And the harder you train the higher the rates of depletion.
Why does glutamine depletion happen so quickly? Because glutamine increases the hydration state of the muscle cells. Hydration of the muscle cells can change rapidly, and once the cells are dehydrated they enter a catabolic state. During times of catabolic stress research has shown that glutamine levels can drop by as much as 50%.

Overtraining will result in less gains, but also higher disease rates, infections and a poor immune system, due to the heavy demands place on the energy reserves of the body. Higher levels of training result in higher stress demands on the body, which lead to a reduction in plasma glutamine levels. Too little glutamine results in muscle loss.

Catabolic states, muscle loss, depletion, cell dehydration and muscle atrophy are phrases that weaken the knees of even the most seasoned of weightlifters or bodybuilders. How can one little supplement that is produced in abundance by the body be responsible for so many concerns?

According to Ronald Klatz, MD, President of the Academy of Anti-Aging Medicine in Chicago, “Glutamine promotes the assimilation of nutrients, regulates protein synthesis, stimulates growth-hormone production and enhances the immune system.”
Weightlifters and bodybuilders need to realize that glutamine is critical for muscle building because it is a nitrogen donor, meaning that it moves the nitrogen around in the body to where it is needed. Anyone that pushes the iron understands that a positive nitrogen balance is a necessary criteria in the effort to gain muscle mass.

Entering the Krebs cycle as a non-carbohydrate source of energy, glutamine converts to glutamate and produces ATP which is an energy molecule. With adequate amounts of glutamine in the body through diet and/or supplementation, little or no muscle is broken down to provide glucose. And, remember, too little glutamine results in muscle atrophy. "

Additional benefits of supplementing with glutamine....

"As the chief source of energy for the intestines, glutamine aids in diseases that effect the lining of the intestines. In addition, it can reverse some of the intestinal damage caused by non-steroidal anti-inflammatories, such as ibuprofen. And in it’s capacity to protect the brain from ammonia toxicity, glutamine is being researched with regard to it’s positive effects on neurodegenerative diseases. As an energy provider to the brain, glutamine is a mood elevator, improves mental performance and helps with long and short term memory.

Glutamine research continues to produce additional benefits of this supplement on a daily basis. With the apparent lack of side effects, it is a supplement that all in the fitness industry should give serious consideration. "

I could spend all day showing you stuff like this that is NOT from any supplement company....but I don't have time...I have read up on what I need to know, what you think is what you think...like I said, everyone has their own opinion and sources for those opinions. ..cheers buddy!
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Last edited by Todd; 20-Feb-03 at 06:20 PM.
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