creatine doesn't give permanent results in the short-term - the big pump is from increased intracellular water pressure. that's why you have to drink so much water when taking it. it can help with short-duration, high-intensity performance (weight-lifting) but doesn't do bupkuss for long-duration exercise like running or jogging.
the results you get from it depend largely on your own natural creatine levels. if you already have high intramuscular creatine levels, you won't get much from
creatine supplementation. taking it with dextrose and/or maltodextrin can increase your uptake.
you're lucky: 20 - 30% of ppl are non-responders, meaning they get nothing from it at all.
i think the stuff your friend was talking about was glutamine, an amino acid that makes up about 60% of your muscle tissue - oral supplementation of glutamine is very ineffective. the best way to increase plasma glutamine levels is to increase your natural glutathione production - glutathione metabolizes into glutamine. you can do that by taking mega-doses of vitamin C - start with 500mg morning and night.
of course, he *could* be talking "glucosamine", but i dont' think that's what you're after, since glucosamine is used to build up and repair
connective tissue and cartilege in joints.