Fizogens' Mass Cycle

[AndrewH]

Thinking about getting it, did some research and found that they said this:


Serving Size: 1 Scoop (23g)
Servings Per Container: 45

Amount Per Serving:
Calories - 56
Total Carbohydrates - 13g (Sugars 0g)
Protein - 4g
Total Fat - 0mg
Sodium - 250mg
Potassium - 250mg
Vitamin B-6 (Pyridoxine HCL) - 15mg
Vitamin B12 (Cyanocobalamin) - 90mcg
Folic Acid - 200mcg
Niacin - 5mg
Magnesium - 500mg
Phosphorus - 950mg
Calcium - 250mg
Mass Cycle Patent Pending Extreme Bulking Agent Mass-Explode:
Mass Explode - 3000g
(Extreme Esterified Creatine Fusion) Creatine Ethyl Carbonate Ester, Creatine Ester Phosphate Sodium, Di-Creatine Orotate
Bulk Onslaught - 2000g
(Glutamine Ester "Swelling" Technology) Glutamine Ethyl Ester HCL, Glutamine Alpha Ketoglutarate, L-Glutamine
Nuke Centrifuse - 790mg
(Nuclear Insulin Driving Agent) 4-Hydroxy-Isoleucine, R+-Alpha-Lipoic Acid, Cinnulin, Di-Potassium Phosphate, Di-Calcium Phosphate, Di-Sodium Phosphate
Cell Shock - 500mg
("Multiple Warhead" DNA/RNA Ammunition) Magnesium Orotate, Potassium Orotate, Di-Arginine Orotate Other Ingredients:
Maltodextrin, Citric Acid, Natural Flavors, Artificial Flavors, Aspartame, Sucralose, Acesulfame K, Silica, FD&C and Red 40.

OK, I know what most of the stuff is, but what is Bulk Onslaught, or Nuke Centrifuse, or Cell Shock? It has what is in there.. but what exactly does it do to the body?

[AndrewH]

Confusion... I wish they could just say what it is and what it does! After an hour's worth of looking for what all the key components were for these things..I still can't tell what it does!

[DaRkAnGel]

Fizogen blast cycle is much better.

[Maxgain]

Originally Posted by AndrewH

Confusion... I wish they could just say what it is and what it does! After an hour's worth of looking for what all the key components were for these things..I still can't tell what it does!

No they cant do that becaus most of that stuff is a pile of crap so they put mad names on it and hope you wont try and check it up.
Come on Bulk Onslaught, or Nuke Centrifuse, or Cell Shock it has to be good.
All that talk has made me hungry for a powersauce bar mmm the power of apples unleashed.

[DaRkAnGel]

Originally Posted by Maxgain

No they cant do that becaus most of that stuff is a pile of crap so they put mad names on it and hope you wont try and check it up.
Come on Bulk Onslaught, or Nuke Centrifuse, or Cell Shock it has to be good.
All that talk has made me hungry for a powersauce bar mmm the power of apples unleashed.

Have u bothered to check out my recomendation? Give it a search.

It wont make you bigger by itself but it will take your workouts to a new place.

[Maxgain]

Sorry if im sceptical but come on

"Enter the weight room battle with a thermonuclear weapon! Detonate our secret atomic pump blaster and then bust up the gym. Blast cycle contains nine unimaginable powerful never before seen pump nuking ingredients. "

"Under the influence of Blast Cycle's battle hardened rage, your gym will soon tremble as it gives witness to your brutal training advance, your insanely powerful weight lifting onslaught, which will help incite a mind-blowing huge pump. Remember; never enter weight room battle outgunned or unarmed. Put a thermonuclear weapon in your training arsenal today and get nuked."

Id be so afraid to be seen buying it like entering a sex shop or soemthing beside my church

[DaRkAnGel]

Go past the marketting bull**** and read the ingredients, lol.

[DaRkAnGel]

I just got some blast cycle so will let you know how it goes.

Max this one is for you: Have you ever heard of the negative effects of glycociamine (guandiniproic acid) ? Just wondering because i remember reading some bad stuff about it but apparently only t-mag has written about this supplement.

[Maxgain]

OK first the studies

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=819853 6&dopt=Abstract
1% beta-GPA in their diet had a significant decrease in Vmax. and a significant decrease in Km for ADP. Thus the hearts from beta-GPA-fed animals may be pathologic, due to a disruption of the creatine kinase energy circuit.

Creatine and Creatinine Metabolism
Finally, feeding of rats and mice with 3-guanidinopropionic acid (GPA), a competitive inhibitor of Cr entry into cells, progressively decreased the concentrations of Cr and PCr in heart and skeletal muscle but had only little influence on the Cr and PCr contents of brain (372). One possible explanation is that the brain contains its own Cr-synthesizing machinery (171). To conclude, the detailed contribution of the various tissues of the body to total Cr biosynthesis as well as the relevance of guanidinoacetate and Cr transport between the tissues are still rather unclear; this is due both to a lack of thorough investigations and to the pronounced species differences observed so far.


Increased growth of brown adipose tissue but its reduced thermogenic activity in creatine-depleted rats fed -guanidinopropionic acid.
Compared to control rats, a marked decrease in the levels of high-energy phosphates, such as phosphocreatine and ATP, was noted in BAT of beta-GPA rats. Conversely, upward trends in other chemical components (DNA, glycogen, and total protein) in BAT as well as an increase in BAT mass were observed in beta-GPA rats, suggesting a tendency to hyperplasia of the BAT

It was suggested that the impairment of BAT thermogenic activity reflects a sparing of ATP in compensation for a reduction in high-energy phosphate levels, with resultant hypothermia


However there is a study to show it reduces glucose levels when some insulin is present thus most likely improves insulins actions supposedly as good as some hypoglycemics thus promoting a greater nutrient uptake by muscles.

Creatine Uptake in Isolated Soleus Muscle:
Kinetics and Dependence on Sodium, but not on Insulin

C.A. WILLOTT, M.E. YOUNG, B. LEIGHTON, G.J. KEMP, E.A. BOEHM,
G.K. RADDA and K. CLARKE

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK

ABSTRACT

The increased use of creatine by athletes as a dietary supplement to improve their physical performance assumes that increased serum creatine levels will increase intracellular skeletal muscle creatine. Despite this common assumption, skeletal muscle creatine uptake awaits full characterization. Consequently, we have investigated. C-labelled creatine uptake in isolated, incubated rat soleus (type 1) muscle preparations at 37° C. We found that the apparent Km for creatine uptake was 73 μM and the Vmax was 77nmol h gww. Creatine uptake was 82% inhibited by 2mM β-guanidinopropionic acid, the structural analogue of creatine. In addition, a decrease in buffer Na concentration, from 145 to 25mM, reduced the rate of C-labelled creatine uptake by 77%, indicating that uptake is largely Na dependent in soleus muscle. Insulin had no effect on the rate of creatine uptake in vitro. The total creatine content was 34% lower, but the rate of creatine uptake in the presence of 100 μM extracellular creatine was 45% higher, in soleus than in extensor digitorum longus (type II) muscle. However, at 1 mM extracellular creatine, the maximal rate of uptake was not significantly different for the two muscle types, implying that soleus muscle has a lower Km for creatine uptake. We suggest that intracellular creatine levels may play a role in the regulation of skeletal muscle creatine uptake.


Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate.
Homocysteine export was significantly increased in the presence of guanidinoacetate. (Glycocyamine) Creatine, however, was without effect. These results suggest that homocysteine metabolism is sensitive to methylation demand imposed by physiological substrates.

[Maxgain]

Ok first off all these 2 substances are different and i never heard of them before today.
However from what I can gather GPA is used as an insulin effect promotor to alllow uptake into muscle cells. However it binds to creatine receptor and as such prevents creatine uptake so as well as the possiblity of problems in tissues that naturally use creatine brain heart etc muscle cells will also be inhibited from its uptake defying the point of creatine and thus confusing me on its addition on whether i am reading it wrong.
Studies have linked it to fat gain and poor oxygen and energy use also.

Glycocyamine is a precursor to creatine. It is based on the theory you can greatly increase natural creatine production by using it where creatine uptake is limited. This is flawed creatine uptake is limited as muscle cells can only hold so much and the same will be for whether it is exogenous or naturally produced.
The study above links it to high homocysteine production which is linked to serious CV disease where creatine is not so it is a much safer option.

Companies are always looking at new ways to increase their share of the huge creatine market and bring out many useless products. The fact is about 3g of creatine a day will cause full saturation of muscles regardless of transporters, adjuvants etc. All these extra are not needed at all. All you need is creatine monohydrate and then maybe some glucose or sodium for optimum intake.

Maxgain

[DaRkAnGel]

The blast cycle was a gift so i am still unsure whether returning is a good idea.

Here is the basic question: how much glycocyamine is actually in the supplement? Blast cycle is mainly a vasodillator (that is really hyped). Does it actually have enough of the substance to impare creatine uptake or are we just looking at an ingredient in the list to impress the customers (not much of it is actually in there due to the miserly nature of supplement companies in general).

So, paraphrased, is there enough of the substance to hinder health/muscle growth or am i safe in at least giving this a trial run?

[kyle!!]

I know this sounds like an uneducated reply but it seems stupid to take all those supps. all I took was a bit of protien powder and I was fine. Also I ate a ****load of good food. Just seems like it would cost alot to use all that stuff and it probably wouldn't help your gains all that much.

[DaRkAnGel]

Not the kind of response i was looking for.

[Maxgain]

I havent seen the amounts or amounts for effects but im sure they wont be loading it in. I say it will offer more benefit on a once off use.

After that though i would look at Kyles advice.

[DaRkAnGel]

Not that im a pro but for the most part my training and diet are pretty spot on. I dont use supplements as crutches, i use them as aids.